Need to know what is your DAW you use. I cant replicate that behaviour on any machine here on different DAWs and apps and running the software per days. This sound like if software crash in your machine. Is the only way the software can disappear from task manager now. If software crash or if user close the software.
Also need to now, if you have some template build, need to share for setup here elephant in the same way, what happens before you detect software crash, what are you doing in your DAW, what plugin try to control, if is 100% random, etc, any info you can provide is useful for try replicate the behaviour, also your windows version, language, keyboard language, model CPU, Ram, your are using standard HD, SSD, Single monitor screen, dual monitor screen?
Using Elephant only mouse modes, MIDI modes, you use hotkeys to change of modes?
Please type in the search box of windows ABOUT, and check version and OS build. Need that info.
Please reply all what you can, Also I think is time to access to your computer to check what happens.
Confirm if possible.